4W5C: Crystal structure analysis of cruzain with three Fragments: 1 (N-(1H-benzimidazol-2-yl)-1,3-dimethyl-pyrazole-4-carboxamide), 6 (2-amino-4,6-difluorobenzothiazole) and 9 (N-(1H-benzimidazol-2-yl)-3-(4-fluorophenyl)-1H-pyrazole-4-carboxamide)

PDB ID: 4W5CDownload
MMDB ID: 128449
PDB Deposition Date: 2014/8/17
Updated in MMDB: 2017/12
Experimental Method:
x-ray diffraction
Resolution: 3.27  Å
Source Organism:
Similar Structures:
Biological Unit for 4W5C: monomeric; determined by software (PISA)
Molecular Components in 4W5C
Label Count Molecule
Protein (1 molecule)
1
Cruzipain
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
N-(1H-benzimidazol-2-yl)-1,3-dimethyl-1H-pyrazole-4-carboxamideN-(1H-benzimidazol-2-yl)-1,3-dimethyl-1H-pyrazole-4-carboxamide
2
1
N-(1H-benzimidazol-2-yl)-3-(4-fluorophenyl)-1H-pyrazole-4-carboxamideN-(1H-benzimidazol-2-yl)-3-(4-fluorophenyl)-1H-pyrazole-4-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303