4V25: Ver-246608, A Novel Pan-isoform Atp Competitive Inhibitor Of Pyruvate Dehydrogenase Kinase, Disrupts Warburg Metabolism And Induces Context- Dependent Cytostasis In Cancer Cells

PDB ID: 4V25Download
MMDB ID: 125287
PDB Deposition Date: 2014/10/6
Updated in MMDB: 2014/12
Experimental Method:
x-ray diffraction
Resolution: 2.6  Å
Source Organism:
Similar Structures:
Biological Unit for 4V25: dimeric; determined by author and by software (PISA)
Molecular Components in 4V25
Label Count Molecule
Proteins (2 molecules)
2
[pyruvate Dehydrogenase (Acetyl-transferring)] Kinase Isozyme 2, Mitochondrial(Gene symbol: PDK2)
Molecule annotation
Chemicals (6 molecules)
1
2
2
2
3
2
* Click molecule labels to explore molecular sequence information.

Citing MMDB
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