4V04: FGFR1 in complex with ponatinib

PDB ID: 4V04Download
MMDB ID: 125506
PDB Deposition Date: 2014/9/10
Updated in MMDB: 2014/12
Experimental Method:
x-ray diffraction
Resolution: 2.12  Å
Source Organism:
Similar Structures:
Biological Unit for 4V04: monomeric; determined by software (PISA)
Molecular Components in 4V04
Label Count Molecule
Protein (1 molecule)
1
Fibroblast Growth Factor Receptor 1 (Fms-related Tyrosine Kinase 2, Pfeiffer Syndrome), Isoform Cra_b
Molecule annotation
Chemicals and Non-standard biopolymers (11 molecules)
1
6
1,2-ETHANEDIOL1,2-ETHANEDIOL
2
1
3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide
3
4
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303