4UWH: Discovery of (2S)-8-((3R)-3-Methylmorpholin-4-yl)-1-(3-methyl-2-oxo- butyl)-2-(trifluoromethyl)-3,4-dihydro-2H-pyrimido(1,2-a)pyrimidin-6- one: a Novel Potent and Selective Inhibitor of Vps34 for the Treatment of Solid Tumors

PDB ID: 4UWHDownload
MMDB ID: 125123
PDB Deposition Date: 2014/8/12
Updated in MMDB: 2014/11
Experimental Method:
x-ray diffraction
Resolution: 1.93  Å
Source Organism:
Similar Structures:
Biological Unit for 4UWH: monomeric; determined by author and by software (PISA)
Molecular Components in 4UWH
Label Count Molecule
Protein (1 molecule)
Phosphatidylinositol 3-kinase Catalytic Subunit Type 3
(Gene symbol: PIK3C3)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
* Click molecule labels to explore molecular sequence information.

Citing MMDB