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4UWD:
HIF prolyl hydroxylase 2 (PHD2/ EGLN1) D315E VARIANT in complex with Mn(II) and N-[(1-chloro-4-hydroxyisoquinolin-3-yl)carbonyl]glycine (IOX3/UN9)
PDB ID:
4UWD
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MMDB ID:
122790
PDB Deposition Date:
2014/8/11
Updated in MMDB:
2014/10
Experimental Method:
x-ray diffraction
Resolution:
1.721 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 4UWD: monomeric; determined by author and by software (PISA)
Molecular Components in 4UWD
Label
Count
Molecule
Protein (1 molecule)
A
1
EGL Nine Homolog 1
(Gene symbol:
EGLN1
)
Chemicals and Non-standard biopolymers (2 molecules)
1
1
MANGANESE (II) ION
2
1
N-[(1-CHLORO-4-HYDROXYISOQUINOLIN-3-YL)CARBONYL]GLYCINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303