4UWD: HIF prolyl hydroxylase 2 (PHD2/ EGLN1) D315E VARIANT in complex with Mn(II) and N-[(1-chloro-4-hydroxyisoquinolin-3-yl)carbonyl]glycine (IOX3/UN9)

PDB ID: 4UWDDownload
MMDB ID: 122790
PDB Deposition Date: 2014/8/11
Updated in MMDB: 2014/10
Experimental Method:
x-ray diffraction
Resolution: 1.721  Å
Source Organism:
Similar Structures:
Biological Unit for 4UWD: monomeric; determined by author and by software (PISA)
Molecular Components in 4UWD
Label Count Molecule
Protein (1 molecule)
1
EGL Nine Homolog 1
(Gene symbol: EGLN1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
MANGANESE (II) IONMANGANESE (II) ION
2
1
N-[(1-CHLORO-4-HYDROXYISOQUINOLIN-3-YL)CARBONYL]GLYCINEN-[(1-CHLORO-4-HYDROXYISOQUINOLIN-3-YL)CARBONYL]GLYCINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303