4UMU: Structure Of Melk In Complex With Inhibitors

PDB ID: 4UMUDownload
MMDB ID: 124209
PDB Deposition Date: 2014/5/21
Updated in MMDB: 2014/10
Experimental Method:
x-ray diffraction
Resolution: 2.02  Å
Source Organism:
Similar Structures:
Biological Unit for 4UMU: monomeric; determined by author and by software (PISA)
Molecular Components in 4UMU
Label Count Molecule
Protein (1 molecule)
1
Maternal Embryonic Leucine Zipper Kinase
(Gene symbol: MELK)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(2-Ethoxy-4-{[3-(Isoquinolin-7-Yl)prop-2-Yn-1-Yl]oxy}phenyl)methanaminium(2-Ethoxy-4-{[3-(Isoquinolin-7-Yl)prop-2-Yn-1-Yl]oxy}phenyl)methanaminium
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303