4UMP: Structure of MELK in complex with inhibitors

PDB ID: 4UMPDownload
MMDB ID: 123703
PDB Deposition Date: 2014/5/20
Updated in MMDB: 2014/10
Experimental Method:
x-ray diffraction
Resolution: 2.3  Å
Source Organism:
Similar Structures:
Biological Unit for 4UMP: dimeric; determined by author and by software (PISA)
Molecular Components in 4UMP
Label Count Molecule
Proteins (2 molecules)
2
Maternal Embryonic Leucine Zipper Kinase
(Gene symbol: MELK)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
3-(isoquinolin-7-yl)prop-2-yn-1-ol3-(isoquinolin-7-yl)prop-2-yn-1-ol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303