4UHX: Human aldehyde oxidase in complex with phthalazine and thioridazine

PDB ID: 4UHXDownload
MMDB ID: 132177
PDB Deposition Date: 2015/3/26
Updated in MMDB: 2015/10
Experimental Method:
x-ray diffraction
Resolution: 2.7  Å
Source Organism:
Similar Structures:
Biological Unit for 4UHX: dimeric; determined by author and by software (PISA)
Molecular Components in 4UHX
Label Count Molecule
Proteins (2 molecules)
2
Aldehyde Oxidase
(Gene symbol: AOX1)
Molecule annotation
Chemicals and Non-standard biopolymers (20 molecules)
1
4
FE2/S2 (INORGANIC) CLUSTERFE2/S2 (INORGANIC) CLUSTER
2
2
PHOSPHONIC ACIDMONO-(2-AMINO-5,6-DIMERCAPTO-4-OXO-3,7,8A,9,10,10A-HEXAHYDRO-4H-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-7-YLMETHYL)ESTERPHOSPHONIC ACIDMONO-(2-AMINO-5,6-DIMERCAPTO-4-OXO-3,7,8A,9,10,10A-HEXAHYDRO-4H-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-7-YLMETHYL)ESTER
3
2
DIOXOTHIOMOLYBDENUM(VI) IONDIOXOTHIOMOLYBDENUM(VI) ION
4
2
FLAVIN-ADENINE DINUCLEOTIDEFLAVIN-ADENINE DINUCLEOTIDE
5
2
phthalazinephthalazine
6
2
10-{2-[(2S)-1-methylpiperidin-2-yl]ethyl}-2-(methylsulfanyl)-10H-phenothiazine10-{2-[(2S)-1-methylpiperidin-2-yl]ethyl}-2-(methylsulfanyl)-10H-phenothiazine
7
2
10-{2-[(2R)-1-methylpiperidin-2-yl]ethyl}-2-(methylsulfanyl)-10H-phenothiazine10-{2-[(2R)-1-methylpiperidin-2-yl]ethyl}-2-(methylsulfanyl)-10H-phenothiazine
8
4
MALONATE IONMALONATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303