4UF0: Crystal structure of JmjC domain of human histone demethylase UTY in complex with epitherapuetic compound 2-(((2-((2-(dimethylamino)ethyl) (ethyl)amino)-2-oxoethyl)amino)methyl)isonicotinic acid

PDB ID: 4UF0Download
MMDB ID: 126097
PDB Deposition Date: 2014/12/22
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.78  Å
Source Organism:
Similar Structures:
Biological Unit for 4UF0: monomeric; determined by author and by software (PISA)
Molecular Components in 4UF0
Label Count Molecule
Protein (1 molecule)
1
Histone Demethylase UTY
(Gene symbol: UTY)
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
1
FE (II) IONFE (II) ION
2
1
2-{[(2-{[(E)-2-(dimethylamino)ethenyl](ethyl)amino}-2-oxoethyl)amino]methyl}pyridine-4-carboxylic acid2-{[(2-{[(E)-2-(dimethylamino)ethenyl](ethyl)amino}-2-oxoethyl)amino]methyl}pyridine-4-carboxylic acid
3
1
ZINC IONZINC ION
4
9
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303