4U8Z: Crystal structure of MST3 with a pyrrolopyrimidine inhibitor (PF-06447475)

PDB ID: 4U8ZDownload
MMDB ID: 127906
PDB Deposition Date: 2014/8/5
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.63  Å
Source Organism:
Similar Structures:
Biological Unit for 4U8Z: monomeric; determined by author and by software (PISA)
Molecular Components in 4U8Z
Label Count Molecule
Protein (1 molecule)
1
Serine/threonine-protein Kinase 24
(Gene symbol: STK24)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
MANGANESE (II) IONMANGANESE (II) ION
2
1
3-[4-(morpholin-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrile3-[4-(morpholin-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrile
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303