4U81: Mek1 Kinase Bound To Small Molecule Inhibitor G659

PDB ID: 4U81Download
MMDB ID: 123484
PDB Deposition Date: 2014/7/31
Updated in MMDB: 2014/10
Experimental Method:
x-ray diffraction
Resolution: 2.7  Å
Source Organism:
Similar Structures:
Biological Unit for 4U81: monomeric; determined by author
Molecular Components in 4U81
Label Count Molecule
Protein (1 molecule)
1
Dual Specificity Mitogen-activated Protein Kinase Kinase 1
(Gene symbol: MAP2K1)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
Magnesium IonMagnesium Ion
2
1
8-[(4-Cyclopropyl-2-Fluorophenyl)amino]-N-(2-Hydroxyethoxy)imidazo[1,5-A]pyridine-7-Carboxamide8-[(4-Cyclopropyl-2-Fluorophenyl)amino]-N-(2-Hydroxyethoxy)imidazo[1,5-A]pyridine-7-Carboxamide
3
1
Phosphoaminophosphonic Acid-Adenylate EsterPhosphoaminophosphonic Acid-Adenylate Ester
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303