4U2K: X-ray structure uridine phosphorylase from Vibrio cholerae in complex with anticancer compound at 2.13 A resolution

PDB ID: 4U2KDownload
MMDB ID: 131241
PDB Deposition Date: 2014/7/17
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.13  Å
Source Organism:
Similar Structures:
Biological Unit for 4U2K: hexameric; determined by author and by software (PISA)
Molecular Components in 4U2K
Label Count Molecule
Proteins (6 molecules)
6
Uridine Phosphorylase
Molecule annotation
Chemicals and Non-standard biopolymers (15 molecules)
1
7
1,2-ETHANEDIOL1,2-ETHANEDIOL
2
2
1-[(2R)-2,3-diaminopropyl]-5-fluoropyrimidine-2,4(1H,3H)-dione1-[(2R)-2,3-diaminopropyl]-5-fluoropyrimidine-2,4(1H,3H)-dione
3
2
GLYCEROLGLYCEROL
4
1
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
5
2
1-[(2S)-2,3-diaminopropyl]-5-fluoropyrimidine-2,4(1H,3H)-dione1-[(2S)-2,3-diaminopropyl]-5-fluoropyrimidine-2,4(1H,3H)-dione
6
1
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303