4U14: Structure of the M3 muscarinic acetylcholine receptor bound to the antagonist tiotropium crystallized with disulfide-stabilized T4 lysozyme (dsT4L)

PDB ID: 4U14Download
MMDB ID: 125112
PDB Deposition Date: 2014/7/15
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 3.57  Å
Source Organism:
Similar Structures:
Biological Unit for 4U14: monomeric; determined by author
Molecular Components in 4U14
Label Count Molecule
Protein (1 molecule)
1
Muscarinic Acetylcholine Receptor M3,endolysin,muscarinic Acetylcholine Receptor M3
(Gene symbol: e)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(1R,2R,4S,5S,7S)-7-{[hydroxy(dithiophen-2-yl)acetyl]oxy}-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.0~2,4~]nonane(1R,2R,4S,5S,7S)-7-{[hydroxy(dithiophen-2-yl)acetyl]oxy}-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.0~2,4~]nonane
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303