4TY6: Factor XIa in complex with the inhibitor 4-{2-[(1S)-1-({[trans-4-(aminomethyl)cyclohexyl]carbonyl}amino)-2-phenylethyl]-1H-imidazol-4-yl}benzamide

PDB ID: 4TY6Download
MMDB ID: 125255
PDB Deposition Date: 2014/7/7
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.85  Å
Source Organism:
Similar Structures:
Biological Unit for 4TY6: dimeric; determined by author and by software (PISA)
Molecular Components in 4TY6
Label Count Molecule
Proteins (2 molecules)
1
Coagulation Factor XI
(Gene symbol: F11)
Molecule annotation
1
Cys-thr-thr-lys-ile-lys-pro
(Gene symbol: F11)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
1
4-{2-[(1S)-1-({[trans-4-(aminomethyl)cyclohexyl]carbonyl}amino)-2-phenylethyl]-1H-imidazol-4-yl}benzamide4-{2-[(1S)-1-({[trans-4-(aminomethyl)cyclohexyl]carbonyl}amino)-2-phenylethyl]-1H-imidazol-4-yl}benzamide
2
1
SULFATE IONSULFATE ION
3
8
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303