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4TWY:
Structure of SARS-3CL protease complex with a phenylbenzoyl (S,R)-N-decalin type inhibitor
PDB ID:
4TWY
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MMDB ID:
127127
PDB Deposition Date:
2014/7/2
Updated in MMDB:
2024/12
Experimental Method:
x-ray diffraction
Resolution:
1.6 Å
Source Organism:
Severe acute respiratory syndrome-related coronavirus
Similar Structures:
VAST+
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Biological Unit for 4TWY: dimeric; determined by author and by software (PISA)
Molecular Components in 4TWY
Label
Count
Molecule
Proteins (2 molecules)
A
A_1
2
3c-like Proteinase
(Gene symbol:
orf1ab
)
Chemicals and Non-standard biopolymers (2 molecules)
1
2
(2S)-2-({[(3S,4aR,8aS)-2-(biphenyl-4-ylcarbonyl)decahydroisoquinolin-3-yl]methyl}amino)-3-(1H-imidazol-5-yl)propanal
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303