4TVG: HIV Protease (PR) dimer in closed form with pepstatin in active site and fragment AK-2097 in the outside/top of flap

PDB ID: 4TVGDownload
MMDB ID: 123472
PDB Deposition Date: 2014/6/26
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.18  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 4TVG: trimeric; determined by author and by software (PISA)
Molecular Components in 4TVG
Label Count Molecule
Proteins (3 molecules)
2
HIV Protease
Molecule annotation
1
Pepstatin
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
3-(morpholin-4-ylmethyl)-1H-indole-6-carboxylic acid3-(morpholin-4-ylmethyl)-1H-indole-6-carboxylic acid
2
1
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303