4TUH: Bcl-xL in complex with inhibitor (Compound 10)

PDB ID: 4TUHDownload
MMDB ID: 123901
PDB Deposition Date: 2014/6/24
Updated in MMDB: 2017/12
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 4TUH: dimeric; determined by author and by software (PISA)
Molecular Components in 4TUH
Label Count Molecule
Proteins (2 molecules)
2
Bcl-2-like Protein 1
(Gene symbol: BCL2L1)
Molecule annotation
Chemicals and Non-standard biopolymers (11 molecules)
1
2
2-[8-(1,3-benzothiazol-2-ylcarbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl]-5-{3-[4-(1H-pyrazolo[3,4-d]pyrimidin-1-yl)phenoxy]propyl}-1,3-thiazole-4-carboxylic acid2-[8-(1,3-benzothiazol-2-ylcarbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl]-5-{3-[4-(1H-pyrazolo[3,4-d]pyrimidin-1-yl)phenoxy]propyl}-1,3-thiazole-4-carboxylic acid
2
8
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
1
ACETATE IONACETATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303