4TRW: Structure of BACE1 complex with a syn-HEA-type inhibitor

PDB ID: 4TRWDownload
MMDB ID: 130490
PDB Deposition Date: 2014/6/18
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.85  Å
Source Organism:
synthetic construct▼
Similar Structures:
Molecular Components in 4TRW
Label Count Molecule
Proteins (6 molecules)
3
Beta-secretase 1
Molecule annotation
3
L-alpha-glutamyl-l-isoleucyl-n-[(2r,3s)-1-{[(1s)-1-carboxybutyl]amino}-2-hydroxy-5-methylhexan-3-yl]-3-thiophen-2-yl-l-alaninamide
Molecule annotation
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303