4TPY: High throughput screening using acoustic droplet ejection to combine protein crystals and chemical libraries on crystallization plates at high density

PDB ID: 4TPYDownload
MMDB ID: 124109
PDB Deposition Date: 2014/6/10
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 1.3  Å
Source Organism:
Similar Structures:
Biological Unit for 4TPY: monomeric; determined by author and by software (PISA)
Molecular Components in 4TPY
Label Count Molecule
Protein (1 molecule)
1
Cationic Trypsin
(Gene symbol: PRSS1)
Molecule annotation
Chemicals and Non-standard biopolymers (42 molecules)
1
1
CALCIUM IONCALCIUM ION
2
6
SODIUM IONSODIUM ION
3
26
BROMIDE IONBROMIDE ION
4
1
BENZAMIDINEBENZAMIDINE
5
1
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
6
7
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303