4TO6: Structure basis of cellular dNTP regulation, SAMHD1-dGTP-dATP-dTTP/dGTP complex

PDB ID: 4TO6Download
MMDB ID: 123968
PDB Deposition Date: 2014/6/5
Updated in MMDB: 2017/12
Experimental Method:
x-ray diffraction
Resolution: 2.33  Å
Source Organism:
Similar Structures:
Biological Unit for 4TO6: tetrameric; determined by author and by software (PISA)
Molecular Components in 4TO6
Label Count Molecule
Proteins (4 molecules)
4
Deoxynucleoside Triphosphate Triphosphohydrolase Samhd1
(Gene symbol: SAMHD1)
Molecule annotation
Chemicals and Non-standard biopolymers (16 molecules)
1
3
THYMIDINE-5'-TRIPHOSPHATETHYMIDINE-5'-TRIPHOSPHATE
2
5
2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE
3
4
2'-DEOXYADENOSINE 5'-TRIPHOSPHATE2'-DEOXYADENOSINE 5'-TRIPHOSPHATE
4
4
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303