4S35: AMPPCP and TMP bound Crystal structure of thymidylate kinase (aq_969) from Aquifex Aeolicus VF5

PDB ID: 4S35Download
MMDB ID: 135892
PDB Deposition Date: 2015/1/26
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 1.55  Å
Source Organism:
Similar Structures:
Biological Unit for 4S35: dimeric; determined by author and by software (PISA)
Molecular Components in 4S35
Label Count Molecule
Proteins (2 molecules)
2
Thymidylate Kinase
(Gene symbol: tmk)
Molecule annotation
Chemicals and Non-standard biopolymers (11 molecules)
1
2
PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTERPHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER
2
2
THYMIDINE-5'-PHOSPHATETHYMIDINE-5'-PHOSPHATE
3
4
MAGNESIUM IONMAGNESIUM ION
4
2
1,2-ETHANEDIOL1,2-ETHANEDIOL
5
1
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303