4S1S: Crystal structure of a VRC01-lineage antibody, 45-VRC01.H5.F-185917, in complex with clade A/E HIV-1 gp120 core

PDB ID: 4S1SDownload
MMDB ID: 128738
PDB Deposition Date: 2015/1/14
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 3.39  Å
Source Organism:
Human immunodeficiency virus 1▼
Similar Structures:
Biological Unit for 4S1S: trimeric; determined by author and by software (PISA)
Molecular Components in 4S1S
Label Count Molecule
Proteins (3 molecules)
1
Clade A/E 93th057 Hiv-1 Gp120 Core
Molecule annotation
1
FAB of Vrc01-lineage Antibody,45-vrc01.h5.f-185917 Heavy Chain
Molecule annotation
1
FAB of Vrc01 Light Chain
Molecule annotation
Chemicals and Non-standard biopolymers (11 molecules)
1
10
2-acetamido-2-deoxy-beta-D-glucopyranose (Link to PubChem not yet available)2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID (Link to PubChem not yet available)4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303