4RX3: A triple mutant in the omega-loop of TEM-1 beta-lactamase changes the substrate profile via a large conformational change and an altered general base for catalysis

PDB ID: 4RX3Download
MMDB ID: 127473
PDB Deposition Date: 2014/12/8
Updated in MMDB: 2017/12
Experimental Method:
x-ray diffraction
Resolution: 1.39  Å
Source Organism:
Similar Structures:
Biological Unit for 4RX3: monomeric; determined by author and by software (PISA)
Molecular Components in 4RX3
Label Count Molecule
Protein (1 molecule)
1
Beta-lactamase TEM
(Gene symbol: bla)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
CITRATE ANIONCITRATE ANION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303