4RWJ: Crystal Structure of FGFR1 (C488A, C584S) in complex with AZD4547 (N-{3-[2-(3,5-DIMETHOXYPHENYL)ETHYL]-1H-PYRAZOL-5-YL}-4-[(3R,5S)-3,5-DIMETHYLPIPERAZIN-1-YL]BENZAMIDE)

PDB ID: 4RWJDownload
MMDB ID: 128734
PDB Deposition Date: 2014/12/4
Updated in MMDB: 2017/12
Experimental Method:
x-ray diffraction
Resolution: 2.489  Å
Source Organism:
Similar Structures:
Biological Unit for 4RWJ: monomeric; determined by author and by software (PISA)
Molecular Components in 4RWJ
Label Count Molecule
Protein (1 molecule)
1
Fibroblast Growth Factor Receptor 1
(Gene symbol: FGFR1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-{3-[2-(3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-5-yl}-4-[(3R,5S)-3,5-dimethylpiperazin-1-yl]benzamideN-{3-[2-(3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-5-yl}-4-[(3R,5S)-3,5-dimethylpiperazin-1-yl]benzamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303