4RV8: Co-Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Cryptosporidium parvum and the inhibitor p131

PDB ID: 4RV8Download
MMDB ID: 125806
PDB Deposition Date: 2014/11/25
Updated in MMDB: 2015/12
Experimental Method:
x-ray diffraction
Resolution: 2.053  Å
Source Organism:
Similar Structures:
Biological Unit for 4RV8: tetrameric; determined by author and by software (PISA)
Molecular Components in 4RV8
Label Count Molecule
Proteins (4 molecules)
4
Inosine-5'-monophosphate Dehydrogenase
Molecule annotation
Chemicals and Non-standard biopolymers (14 molecules)
1
4
INOSINIC ACIDINOSINIC ACID
2
4
1-(2-{3-[(1E)-N-(2-aminoethoxy)ethanimidoyl]phenyl}propan-2-yl)-3-(4-chloro-3-nitrophenyl)urea1-(2-{3-[(1E)-N-(2-aminoethoxy)ethanimidoyl]phenyl}propan-2-yl)-3-(4-chloro-3-nitrophenyl)urea
3
4
GLYCEROLGLYCEROL
4
2
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303