4RU9: Crystal structure of human DNA polymerase eta inserting dCMPNPP opposite a MeFapy-dG adducted DNA template

PDB ID: 4RU9Download
MMDB ID: 131394
PDB Deposition Date: 2014/11/18
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 2.65  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 4RU9: trimeric; determined by author and by software (PISA)
Molecular Components in 4RU9
Label Count Molecule
Protein (1 molecule)
1
DNA Polymerase ETA
Molecule annotation
Nucleotides(2 molecules)
1
Nucleic Acids Template: Cat(mf7)atgacgct
Molecule annotation
1
Nucleic Acids Primar: Agcgtcat
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine
2
2
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303