4RT7: Crystal Structure Of Flt3 With A Small Molecule Inhibitor

PDB ID: 4RT7Download
MMDB ID: 128730
PDB Deposition Date: 2014/11/13
Updated in MMDB: 2015/06
Experimental Method:
x-ray diffraction
Resolution: 3.1  Å
Source Organism:
Similar Structures:
Biological Unit for 4RT7: dimeric; determined by software (PISA)
Molecular Components in 4RT7
Label Count Molecule
Proteins (2 molecules)
2
Receptor-type Tyrosine-protein Kinase Flt3
(Gene symbol: FLT3)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morpholin-4-Yl)ethoxy]imidazo[2,1-B][1,3]benzothiazol-2-Yl}phenyl)urea1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morpholin-4-Yl)ethoxy]imidazo[2,1-B][1,3]benzothiazol-2-Yl}phenyl)urea
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303