4RRX: Crystal Structure of Apo Murine V89W Cyclooxygenase-2 Complexed with Lumiracoxib

PDB ID: 4RRXDownload
MMDB ID: 128399
PDB Deposition Date: 2014/11/6
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 2.78  Å
Source Organism:
Similar Structures:
Biological Unit for 4RRX: dimeric; determined by author and by software (PISA)
Molecular Components in 4RRX
Label Count Molecule
Proteins (2 molecules)
2
Prostaglandin G/H Synthase 2
(Gene symbol: Ptgs2)
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
8
2-acetamido-2-deoxy-beta-D-glucopyranose (Link to PubChem not yet available)2-acetamido-2-deoxy-beta-D-glucopyranose
2
2
octyl beta-D-glucopyranoside (Link to PubChem not yet available)octyl beta-D-glucopyranoside
3
2
{2-[(2-chloro-6-fluorophenyl)amino]-5-methylphenyl}acetic acid (Link to PubChem not yet available){2-[(2-chloro-6-fluorophenyl)amino]-5-methylphenyl}acetic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303