4RLS: Lactate Dehydrogenase In Complex With Inhibitor Compound 47

PDB ID: 4RLSDownload
MMDB ID: 124705
PDB Deposition Date: 2014
Updated in MMDB: 2014/11
Experimental Method:
x-ray diffraction
Resolution: 1.91  Å
Source Organism:
Similar Structures:
Biological Unit for 4RLS: tetrameric; determined by author and by software (PISA)
Molecular Components in 4RLS
Label Count Molecule
Proteins (4 molecules)
4
L-lactate Dehydrogenase a Chain
(Gene symbol: LDHA)
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
4
1,4-Dihydronicotinamide Adenine Dinucleotide1,4-Dihydronicotinamide Adenine Dinucleotide
2
2
Sulfate IonSulfate Ion
3
2
(2s)-2-Hydroxypropanoic Acid(2s)-2-Hydroxypropanoic Acid
4
1
(1r)-5'-[(2-Chlorophenyl)sulfanyl]-4'-Hydroxy-2,3-Dihydrospiro[indene-1,2'-Pyran]-6'(3'h)-One(1r)-5'-[(2-Chlorophenyl)sulfanyl]-4'-Hydroxy-2,3-Dihydrospiro[indene-1,2'-Pyran]-6'(3'h)-One
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303