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4RJ6:
EGFR kinase (T790M/L858R) with inhibitor compound 4
PDB ID:
4RJ6
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MMDB ID:
125082
PDB Deposition Date:
2014/10/8
Updated in MMDB:
2014/12
Experimental Method:
x-ray diffraction
Resolution:
2.7 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 4RJ6: monomeric; determined by author and by software (PISA)
Molecular Components in 4RJ6
Label
Count
Molecule
Protein (1 molecule)
A
1
Epidermal Growth Factor Receptor
(Gene symbol:
EGFR
)
Chemicals and Non-standard biopolymers (2 molecules)
1
1
SULFATE ION
2
1
N-[2-(4-methoxypiperidin-1-yl)pyrimidin-4-yl]-2-(1H-pyrazol-4-yl)-3H-imidazo[4,5-c]pyridin-6-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303