4RHY: Crystal structures of Mycobacterium tuberculosis 6-oxopurine phosphoribosyltransferase which is a potential target for drug development against this disease

PDB ID: 4RHYDownload
MMDB ID: 129444
PDB Deposition Date: 2014/10/3
Updated in MMDB: 2015/06
Experimental Method:
x-ray diffraction
Resolution: 2.3196  Å
Source Organism:
Similar Structures:
Biological Unit for 4RHY: tetrameric; determined by author
Molecular Components in 4RHY
Label Count Molecule
Proteins (4 molecules)
4
Hypoxanthine-guanine Phosphoribosyltransferase
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
8
MAGNESIUM IONMAGNESIUM ION
2
4
[2-({2-[bis(2-phosphonoethyl)amino]ethyl}[2-(6-oxo-3,6-dihydro-9H-purin-9-yl)ethyl]amino)ethyl]phosphonic acid[2-({2-[bis(2-phosphonoethyl)amino]ethyl}[2-(6-oxo-3,6-dihydro-9H-purin-9-yl)ethyl]amino)ethyl]phosphonic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303