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4RHU:
Crystal structures of Mycobacterium tuberculosis 6-oxopurine phosphoribosyltransferase which is a potential target for drug development against this disease
PDB ID:
4RHU
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MMDB ID:
129442
PDB Deposition Date:
2014/10/3
Updated in MMDB:
2023/09
Experimental Method:
x-ray diffraction
Resolution:
2.573 Å
Source Organism:
Mycobacterium tuberculosis H37Rv
Similar Structures:
VAST+
Download sequence data
Biological Unit for 4RHU: tetrameric; determined by author
Molecular Components in 4RHU
Label
Count
Molecule
Proteins (4 molecules)
A
B
C
D
4
Hypoxanthine-guanine Phosphoribosyltransferase HPT
Chemicals and Non-standard biopolymers (9 molecules)
1
2
{[(2R)-3-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)propane-1,2-diyl]bis(oxyethane-2,1-diyl)}bis(phosphonic acid)
2
5
MAGNESIUM ION
3
2
{[(2S)-3-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)propane-1,2-diyl]bis(oxyethane-2,1-diyl)}bis(phosphonic acid)
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303