4RE9: Crystal structure of human insulin degrading enzyme (IDE) in complex with compound 71290

PDB ID: 4RE9Download
MMDB ID: 133010
PDB Deposition Date: 2014/9/22
Updated in MMDB: 2015/10
Experimental Method:
x-ray diffraction
Resolution: 2.908  Å
Source Organism:
Similar Structures:
Biological Unit for 4RE9: monomeric; determined by software (PISA)
Molecular Components in 4RE9
Label Count Molecule
Protein (1 molecule)
1
Insulin-degrading Enzyme
(Gene symbol: IDE)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
1
ZINC IONZINC ION
2
1
4-fluoro-N-({1-[(2R)-4-(hydroxyamino)-1-(naphthalen-2-yl)-4-oxobutan-2-yl]-1H-1,2,3-triazol-5-yl}methyl)benzamide4-fluoro-N-({1-[(2R)-4-(hydroxyamino)-1-(naphthalen-2-yl)-4-oxobutan-2-yl]-1H-1,2,3-triazol-5-yl}methyl)benzamide
3
1
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
4
6
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
5
1
PENTAETHYLENE GLYCOLPENTAETHYLENE GLYCOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303