4R7I: Crystal structure of FMS kinase domain with a small molecular inhibitor, GLEEVEC

PDB ID: 4R7IDownload
MMDB ID: 131625
PDB Deposition Date: 2014/8/27
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 2.75  Å
Source Organism:
Similar Structures:
Biological Unit for 4R7I: monomeric; determined by author
Molecular Components in 4R7I
Label Count Molecule
Protein (1 molecule)
1
Macrophage Colony-stimulating Factor 1 Receptor
(Gene symbol: CSF1R)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303