4R6E: Human artd1 (parp1) - catalytic domain in complex with inhibitor niraparib

PDB ID: 4R6EDownload
MMDB ID: 132359
PDB Deposition Date: 2014/8/25
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.2  Å
Source Organism:
Similar Structures:
Biological Unit for 4R6E: monomeric; determined by author
Molecular Components in 4R6E
Label Count Molecule
Protein (1 molecule)
1
Poly [adp-ribose] Polymerase 1
(Gene symbol: PARP1)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide
2
1
SULFATE IONSULFATE ION
3
1
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303