4R5T: Structure of the m1 alanylaminopeptidase from malaria complexed with a hydroxamic acid-based inhibitor

PDB ID: 4R5TDownload
MMDB ID: 124366
PDB Deposition Date: 2014/8/22
Updated in MMDB: 2014/11
Experimental Method:
x-ray diffraction
Resolution: 1.98  Å
Source Organism:
Similar Structures:
Biological Unit for 4R5T: monomeric; determined by author and by software (PISA)
Molecular Components in 4R5T
Label Count Molecule
Protein (1 molecule)
1
M1 Family Aminopeptidase
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
1
ZINC ION (Link to PubChem not yet available)ZINC ION
2
2
DIMETHYL SULFOXIDE (Link to PubChem not yet available)DIMETHYL SULFOXIDE
3
8
GLYCEROL (Link to PubChem not yet available)GLYCEROL
4
1
tert-butyl {(1S)-2-(hydroxyamino)-2-oxo-1-[4-(1H-pyrazol-1-yl)phenyl]ethyl}carbamate (Link to PubChem not yet available)tert-butyl {(1S)-2-(hydroxyamino)-2-oxo-1-[4-(1H-pyrazol-1-yl)phenyl]ethyl}carbamate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303