4R5S: Crystal structure of EGFR 696-1022 L858R in complex with FIIN-3

PDB ID: 4R5SDownload
MMDB ID: 124694
PDB Deposition Date: 2014/8/22
Updated in MMDB: 2014/11
Experimental Method:
x-ray diffraction
Resolution: 3.001  Å
Source Organism:
Similar Structures:
Biological Unit for 4R5S: monomeric; determined by author and by software (PISA)
Molecular Components in 4R5S
Label Count Molecule
Protein (1 molecule)
Epidermal Growth Factor Receptor
(Gene symbol: EGFR)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
N-[4-({[(2,6-dichloro-3,5-dimethoxyphenyl)carbamoyl](6-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino}methyl)phenyl]propanamide (Link to PubChem not yet available)N-[4-({[(2,6-dichloro-3,5-dimethoxyphenyl)carbamoyl](6-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino}methyl)phenyl]propanamide
* Click molecule labels to explore molecular sequence information.

Citing MMDB