4QZ4: yCP beta5-A49S mutant in complex with the epoxyketone inhibitor ONX 0914

PDB ID: 4QZ4Download
MMDB ID: 126693
PDB Deposition Date: 2014/7/27
Updated in MMDB: 2022/11
Experimental Method:
x-ray diffraction
Resolution: 3  Å
Source Organism:
Similar Structures:
Biological Unit for 4QZ4: 28-meric; determined by author and by software (PISA)
Molecular Components in 4QZ4
Label Count Molecule
Proteins (28 molecules)
2
Proteasome Subunit Alpha Type-2
(Gene symbol: PRE8)
Molecule annotation
2
Proteasome Subunit Alpha Type-3
(Gene symbol: PRE9)
Molecule annotation
2
Proteasome Subunit Alpha Type-4
(Gene symbol: PRE6)
Molecule annotation
2
Proteasome Subunit Alpha Type-5
(Gene symbol: PUP2)
Molecule annotation
2
Proteasome Subunit Alpha Type-6
(Gene symbol: PRE5)
Molecule annotation
2
Probable Proteasome Subunit Alpha Type-7
(Gene symbol: PRE10)
Molecule annotation
2
Proteasome Subunit Alpha Type-1
(Gene symbol: SCL1)
Molecule annotation
2
Proteasome Subunit Beta Type-2
(Gene symbol: PUP1)
Molecule annotation
2
Proteasome Subunit Beta Type-3
(Gene symbol: PUP3)
Molecule annotation
2
Proteasome Subunit Beta Type-4
(Gene symbol: PRE1)
Molecule annotation
2
Proteasome Subunit Beta Type-5
(Gene symbol: PRE2)
Molecule annotation
2
Proteasome Subunit Beta Type-6
(Gene symbol: PRE7)
Molecule annotation
2
Proteasome Subunit Beta Type-7
(Gene symbol: PRE4)
Molecule annotation
2
Proteasome Subunit Beta Type-1
(Gene symbol: PRE3)
Molecule annotation
Chemicals and Non-standard biopolymers (17 molecules)
7
MAGNESIUM ION (Link to PubChem not yet available)MAGNESIUM ION
2
CHLORIDE ION (Link to PubChem not yet available)CHLORIDE ION
6
1,2,4-trideoxy-4-methyl-2-{[N-(morpholin-4-ylacetyl)-L-alanyl-O-methyl-L-tyrosyl]amino}-1-phenyl-D-xylitol (Link to PubChem not yet available)1,2,4-trideoxy-4-methyl-2-{[N-(morpholin-4-ylacetyl)-L-alanyl-O-methyl-L-tyrosyl]amino}-1-phenyl-D-xylitol
2
2-(N-MORPHOLINO)-ETHANESULFONIC ACID (Link to PubChem not yet available)2-(N-MORPHOLINO)-ETHANESULFONIC ACID
* Click molecule labels to explore molecular sequence information.

Citing MMDB