4QY3: The Crystal Structure Of The Complex Of Hcaii With An Ortho- Substituted Benzoic Acid

Citation:
Abstract
A structural study of the adduct which 2-benzylsulfinylbenzoic acid forms with human carbonic anhydrase II is reported, showing a binding mode completely different from any other class of carbonic anhydrase inhibitors investigated so far; this carboxylate binds in a pocket situated out of the enzyme active site.
PDB ID: 4QY3Download
MMDB ID: 125226
PDB Deposition Date: 2014/7/23
Updated in MMDB: 2014/12
Experimental Method:
x-ray diffraction
Resolution: 1.5  Å
Source Organism:
Similar Structures:
Biological Unit for 4QY3: monomeric; determined by author and by software (PISA)
Molecular Components in 4QY3
Label Count Molecule
Protein (1 molecule)
1
Carbonic Anhydrase 2(Gene symbol: CA2)
Molecule annotation
Chemicals (3 molecules)
1
1
2
1
3
1
* Click molecule labels to explore molecular sequence information.

Citing MMDB
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