4QXS: Crystal structure of human FPPS in complex with WC01088

PDB ID: 4QXSDownload
MMDB ID: 127277
PDB Deposition Date: 2014/7/21
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Similar Structures:
Biological Unit for 4QXS: dimeric; determined by author and by software (PISA)
Molecular Components in 4QXS
Label Count Molecule
Proteins (2 molecules)
2
Farnesyl Pyrophosphate Synthase
(Gene symbol: FDPS)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
4
PHOSPHATE ION (Link to PubChem not yet available)PHOSPHATE ION
2
2
(2-{2-[(2S)-3-methylbutan-2-yl]-5-phenyl-1H-indol-3-yl}ethane-1,1-diyl)bis(phosphonic acid) (Link to PubChem not yet available)(2-{2-[(2S)-3-methylbutan-2-yl]-5-phenyl-1H-indol-3-yl}ethane-1,1-diyl)bis(phosphonic acid)
3
2
GLYCEROL (Link to PubChem not yet available)GLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303