4QSI: Crystal structure of human carbonic anhydrase isozyme II with 5-{[(4-tert-buthyl-6-oxo-1,6-dihydropyrimidin-2-yl)thio]acetyl}-2-chlorobenzenesulfonamide

PDB ID: 4QSIDownload
MMDB ID: 126294
PDB Deposition Date: 2014/7/4
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 1.95  Å
Source Organism:
Similar Structures:
Biological Unit for 4QSI: monomeric; determined by author and by software (PISA)
Molecular Components in 4QSI
Label Count Molecule
Protein (1 molecule)
1
Carbonic Anhydrase 2
(Gene symbol: CA2)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
ZINC IONZINC ION
2
1
2-(N-MORPHOLINO)-ETHANESULFONIC ACID2-(N-MORPHOLINO)-ETHANESULFONIC ACID
3
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
4
1
SODIUM IONSODIUM ION
5
1
5-{[(4-tert-butyl-6-oxo-1,6-dihydropyrimidin-2-yl)sulfanyl]acetyl}-2-chlorobenzenesulfonamide5-{[(4-tert-butyl-6-oxo-1,6-dihydropyrimidin-2-yl)sulfanyl]acetyl}-2-chlorobenzenesulfonamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303