4QQU: Crystal structure of the cobalamin-independent methionine synthase enzyme in a closed conformation

PDB ID: 4QQUDownload
MMDB ID: 126053
PDB Deposition Date: 2014/6/29
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.98  Å
Source Organism:
Similar Structures:
Biological Unit for 4QQU: monomeric; determined by author and by software (PISA)
Molecular Components in 4QQU
Label Count Molecule
Protein (1 molecule)
1
5-methyltetrahydropteroyltriglutamate--homocysteine Methyltransferase
(Gene symbol: MET6)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
2-AMINO-4-MERCAPTO-BUTYRIC ACID2-AMINO-4-MERCAPTO-BUTYRIC ACID
2
1
ZINC IONZINC ION
3
2
PHOSPHATE IONPHOSPHATE ION
4
1
N-[4-({[(6S)-2-amino-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-gamma-glutamyl-L-gamma-glutamyl-L-glutamic acidN-[4-({[(6S)-2-amino-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-gamma-glutamyl-L-gamma-glutamyl-L-glutamic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303