4QHC: Structure of M.Tuberculosis Betalactamase (Blac) with inhibitor having novel mechanism

PDB ID: 4QHCDownload
MMDB ID: 131061
PDB Deposition Date: 2014/5/28
Updated in MMDB: 2015/10
Experimental Method:
x-ray diffraction
Resolution: 1.899  Å
Source Organism:
Similar Structures:
Biological Unit for 4QHC: monomeric; determined by author and by software (PISA)
Molecular Components in 4QHC
Label Count Molecule
Protein (1 molecule)
1
Beta-lactamase
(Gene symbol: blaC)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
(3R,6R,7S)-7-[(2R,3aR)-hexahydropyrazolo[1,5-c][1,3]thiazin-2-yl]-6-(hydroxymethyl)-1,4-thiazepane-3-carboxylic acid(3R,6R,7S)-7-[(2R,3aR)-hexahydropyrazolo[1,5-c][1,3]thiazin-2-yl]-6-(hydroxymethyl)-1,4-thiazepane-3-carboxylic acid
2
2
PHOSPHATE IONPHOSPHATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303