4QCL: Crystal structure of the catalytic core of human DNA polymerase alpha in ternary complex with an RNA-primed DNA template and dCTP

PDB ID: 4QCLDownload
MMDB ID: 125062
PDB Deposition Date: 2014/5/12
Updated in MMDB: 2014/11
Experimental Method:
x-ray diffraction
Resolution: 2.2  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 4QCL: trimeric; determined by author and by software (PISA)
Molecular Components in 4QCL
Label Count Molecule
Protein (1 molecule)
1
DNA Polymerase Alpha Catalytic Subunit
Molecule annotation
Nucleotide(1 molecule)
1
DNA Template
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
B
1
RNA PRIMER
1
1
2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE
2
1
MAGNESIUM IONMAGNESIUM ION
3
3
ZINC IONZINC ION
4
1
POTASSIUM IONPOTASSIUM ION
5
1
PENTAETHYLENE GLYCOLPENTAETHYLENE GLYCOL
6
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303