4Q78: Structure-assisted design of carborane-based inhibitors of carbonic anhydrase

PDB ID: 4Q78Download
MMDB ID: 127870
PDB Deposition Date: 2014/4/24
Updated in MMDB: 2024/03
Experimental Method:
x-ray diffraction
Resolution: 1  Å
Source Organism:
Similar Structures:
Biological Unit for 4Q78: monomeric; determined by author and by software (PISA)
Molecular Components in 4Q78
Label Count Molecule
Protein (1 molecule)
1
Carbonic Anhydrase 2
(Gene symbol: CA2)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
ZINC IONZINC ION
2
1
1-(sulfamoylamino)methyl-1,2-dicarba-closo-dodecaborane1-(sulfamoylamino)methyl-1,2-dicarba-closo-dodecaborane
3
2
MERCURIBENZOIC ACIDMERCURIBENZOIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303