4Q6E: Crystal structure of human carbonic anhydrase isozyme II with 4-{[3-(3,5-Dimethyl-1H-pyrazol-1-yl)-3-oxopropyl]amino}benzene-1-sulfonamide

PDB ID: 4Q6EDownload
MMDB ID: 125061
PDB Deposition Date: 2014/4/22
Updated in MMDB: 2014/11
Experimental Method:
x-ray diffraction
Resolution: 1.12  Å
Source Organism:
Similar Structures:
Biological Unit for 4Q6E: monomeric; determined by author and by software (PISA)
Molecular Components in 4Q6E
Label Count Molecule
Protein (1 molecule)
1
Carbonic Anhydrase 2
(Gene symbol: CA2)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
ZINC IONZINC ION
2
1
BICINEBICINE
3
2
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
4
1
4-{[3-(3,5-dimethyl-1H-pyrazol-1-yl)-3-oxopropyl]amino}benzenesulfonamide4-{[3-(3,5-dimethyl-1H-pyrazol-1-yl)-3-oxopropyl]amino}benzenesulfonamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303