4Q5V: Crystal structure of the catalytic core of human DNA polymerase alpha in ternary complex with an RNA-primed DNA template and aphidicolin

PDB ID: 4Q5VDownload
MMDB ID: 125059
PDB Deposition Date: 2014/4/17
Updated in MMDB: 2014/12
Experimental Method:
x-ray diffraction
Resolution: 2.52  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 4Q5V: trimeric; determined by software (PISA)
Molecular Components in 4Q5V
Label Count Molecule
Protein (1 molecule)
1
DNA Polymerase Alpha Catalytic Subunit
Molecule annotation
Nucleotide(1 molecule)
1
DNA Template
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
B
1
RNA primer
1
1
(3R,4R,4aR,6aS,8R,9R,11aS,11bS)-4,9-bis(hydroxymethyl)-4,11b-dimethyltetradecahydro-8,11a-methanocyclohepta[a]naphthale ne-3,9-diol(3R,4R,4aR,6aS,8R,9R,11aS,11bS)-4,9-bis(hydroxymethyl)-4,11b-dimethyltetradecahydro-8,11a-methanocyclohepta[a]naphthale ne-3,9-diol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303