4Q5M: D30N tethered HIV-1 protease dimer/saquinavir complex

PDB ID: 4Q5MDownload
MMDB ID: 128383
PDB Deposition Date: 2014/4/17
Updated in MMDB: 2017/09
Experimental Method:
x-ray diffraction
Resolution: 1.795  Å
Source Organism:
Similar Structures:
Biological Unit for 4Q5M: monomeric; determined by author and by software (PISA)
Molecular Components in 4Q5M
Label Count Molecule
Protein (1 molecule)
1
Protease
(Gene symbol: gag-pol)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(2S)-N-[(2S,3R)-4-[(2S,3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1 -phenyl-butan-2-yl]-2-(quinolin-2-ylcarbonylamino)butanediamide (Link to PubChem not yet available)(2S)-N-[(2S,3R)-4-[(2S,3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1 -phenyl-butan-2-yl]-2-(quinolin-2-ylcarbonylamino)butanediamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303