4Q1F: Human dCK C4S-S74E mutant in complex with UDP and the inhibitor 12R {N-{2-[5-(4-{(1R)-1-[(4,6-diaminopyrimidin-2-yl)sulfanyl]ethyl}-5-methyl-1,3-thiazol-2-yl)-2-methoxyphenoxy]ethyl}methanesulfonamide}

PDB ID: 4Q1FDownload
MMDB ID: 124485
PDB Deposition Date: 2014/4/3
Updated in MMDB: 2014/12
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 4Q1F: dimeric; determined by author and by software (PISA)
Molecular Components in 4Q1F
Label Count Molecule
Proteins (2 molecules)
2
Deoxycytidine Kinase
(Gene symbol: DCK)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
URIDINE-5'-DIPHOSPHATE (Link to PubChem not yet available)URIDINE-5'-DIPHOSPHATE
2
2
N-{2-[5-(4-{(1R)-1-[(4,6-diaminopyrimidin-2-yl)sulfanyl]ethyl}-5-methyl-1,3-thiazol-2-yl)-2-methoxyphenoxy]ethyl}methanesulfonamide (Link to PubChem not yet available)N-{2-[5-(4-{(1R)-1-[(4,6-diaminopyrimidin-2-yl)sulfanyl]ethyl}-5-methyl-1,3-thiazol-2-yl)-2-methoxyphenoxy]ethyl}methanesulfonamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303