4Q1E: Human Dck C4s-s74e Mutant In Complex With Udp And The Inhibitor 10 {2- {[(1r/s)-1-{2-[3-(2-fluoroethoxy)-4-methoxyphenyl]-5-methyl-1,3- Thiazol 4-yl}ethyl]sulfanyl}pyrimidine-4,6-diamine}

PDB ID: 4Q1EDownload
MMDB ID: 124484
PDB Deposition Date: 2014/4/3
Updated in MMDB: 2014/12
Experimental Method:
x-ray diffraction
Resolution: 1.85  Å
Source Organism:
Similar Structures:
Biological Unit for 4Q1E: dimeric; determined by author and by software (PISA)
Molecular Components in 4Q1E
Label Count Molecule
Proteins (2 molecules)
2
Deoxycytidine Kinase
(Gene symbol: DCK)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
2
(R)-2-((1-(2-(3-(2-Fluoroethoxy)-4-Methoxyphenyl)-5-Methylthiazol-4-Yl)ethyl)thio)pyrimidine-4,6-Diamine(R)-2-((1-(2-(3-(2-Fluoroethoxy)-4-Methoxyphenyl)-5-Methylthiazol-4-Yl)ethyl)thio)pyrimidine-4,6-Diamine
2
2
(S)-2-((1-(2-(3-(2-Fluoroethoxy)-4-Methoxyphenyl)-5-Methylthiazol-4-Yl)ethyl)thio)pyrimidine-4,6-Diamine(S)-2-((1-(2-(3-(2-Fluoroethoxy)-4-Methoxyphenyl)-5-Methylthiazol-4-Yl)ethyl)thio)pyrimidine-4,6-Diamine
3
2
Uridine-5'-DiphosphateUridine-5'-Diphosphate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303